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Factors Associated with Antiretroviral Therapy Adherence Among a Community-Based Sample of Sexual Minority Older Adults with HIV
This study utilized a stochastic search variable selection (SVSS) approach to explore potential psychosocial and structural factors associated with HIV-related health outcomes among a community-based sample of older sexual minorities (N  = 150) in South Florida, an U.S. HIV-epidemic epicenter. After SVSS, a forward entry regression approach suggested unstable housing, illicit substance use, current nicotine use, and depression were all associated with poorer ART adherence among older sexual minority adults living with HIV. No a ssociations between potential correlates and biological measures of HIV disease severity wer...
Source: AIDS and Behavior - September 23, 2023 Category: Infectious Diseases Source Type: research

Metal-Free Janus α- and β-SiCP2: Designing Stable and Efficient Two-dimensional Semiconductors for Water Splitting
In this study, based on the first-principles theory,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 23, 2023 Category: Chemistry Authors: Yanfu Zhao Source Type: research

Background free in vivo29Si MR imaging with hyperpolarized PEGylated silicon nanoparticles
This study demonstrated the potential of 50 nm PEGylated Si NPs for high-resolutionin vivo29Si MR imaging, emphasizing their biocompatibility and water dispersibility. The acquisition of in vivo Si... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - September 23, 2023 Category: Chemistry Authors: Seung-Hyun Yang Source Type: research

Good Oral Health Linked to Improved Survival in Head & Neck Cancer
FRIDAY, Sept. 22, 2023 -- For patients with head and neck squamous cell carcinoma, good oral health is associated with improved survival, according to a study published online Sept. 19 in the Journal of the National Cancer Institute. Jason Tasoulas,...
Source: Drugs.com - Pharma News - September 22, 2023 Category: Pharmaceuticals Source Type: news

A Call for Matching Donors for the LEV Foundation " Robust Mouse Rejuvenation 2 " Fundraiser
The Longevity Escape Velocity (LEV) Foundation was founded by Aubrey de Grey to address an important missing aspect of the ongoing work to produce treatments that target the underlying mechanisms of aging. While the research and development community has made sizable strides in the past decade, and the first rejuvenation therapies now exist in at least prototype form, it remains the case that next to no-one is conducting combination studies that use two or more of these interventions. When considering therapies that can repair forms of the cell and tissue damage that cause aging, it seems plausible that two different thera...
Source: Fight Aging! - September 22, 2023 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

Computational NMR Investigation of Mixed-Metal (Al,Sc)-MIL-53 and its Phase Transitions
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Zachary Davis, Emma A L Borthwick, Russell Morris, Sharon Elizabeth Ashbrook Compositionally complex metal-organic frameworks (MOFs) have properties that depend on local structure that is often difficult to characterise. In this paper a density functional theory (DFT) computational study of mixed-metal... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 22, 2023 Category: Chemistry Authors: Zachary Davis Source Type: research

Effects of square spatial periodic forcing on oscillatory hexagon patterns in coupled reaction –diffusion systems
Phys. Chem. Chem. Phys., 2023, Advance Article DOI: 10.1039/D3CP02464D, PaperWeili Fan, Fengna Ma, Yuan Tong, Qian Liu, Ruoqi Liu, Yafeng He, Fucheng Liu Our study reports the response of oscillatory Turing patterns in coupled reaction diffusion systems to external spatial forcing. The findings provide new insight into pattern formation in layered media. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - September 22, 2023 Category: Chemistry Authors: Weili Fan Source Type: research

Observation of An Electron-Precise Metal Boryne Complex: Bi ≡BHπΠ
This study uncovers a simple electron-precise metal boryne complex, [Bi ≡BH]−, which is produced within an ion trap through... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - September 22, 2023 Category: Chemistry Authors: Han-Wen Gao Source Type: research

Second-line tests in the differential diagnosis of neoplastic and non-neoplastic hypercortisolism: a systematic review and meta-analysis
DiscussionBoth Dex-CRH and Desmopressin tests can be valid tools in helping discrimination between NNH/pCS and CS. Further studies are needed on this topic, possibly focusing on mild Cushing ’s Disease and well-characterized NNH/pCS patients.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022359774, identifier CRD42022359774.
Source: Journal of Endocrinological Investigation - September 22, 2023 Category: Endocrinology Source Type: research

The role of miR-139-5p in radioiodine-resistant thyroid cancer
ConclusionsOur study provides evidence of miR-139-5p involvement in iodine uptake metabolism and suggests its possible role as a therapeutic target in restoring iodine uptake in RAI-refractory DTC.
Source: Journal of Endocrinological Investigation - September 22, 2023 Category: Endocrinology Source Type: research

Oxytocin treatment for core symptoms in children with autism spectrum disorder: a systematic review and meta-analysis
ConclusionWhile the therapeutic value of oxytocin in treating core symptoms of ASD in children is not fully established, the results of this meta-analysis indicate a potential moderate effect. However, further studies with larger sample sizes and more robust RCTs are needed to directly demonstrate the efficacy of oxytocin. Future research should also focus on effect size and outcome evaluation accuracy while minimizing bias in RCT experiments.
Source: European Journal of Clinical Pharmacology - September 22, 2023 Category: Drugs & Pharmacology Source Type: research

LABA/LAMA versus LABA/ICS fixed-dose combinations in the prevention of COPD exacerbations: a modeling analysis of literature aggregate data
ConclusionsThis study showed that not all LABA/LAMA FDCs were superior to LABA/ICS FDCs in safety and in preventing moderate or severe exacerbations in patients with stable COPD, providing important quantitative information for COPD-related guidelines.
Source: European Journal of Clinical Pharmacology - September 22, 2023 Category: Drugs & Pharmacology Source Type: research

Dipeptidyl-peptidase-4 inhibitors have anti-inflammatory effects in patients with type 2 diabetes
ConclusionThis meta-analysis demonstrated that DPP-4 inhibitors can significantly attenuate low-grade inflammatory state in patients with T2DM. In addition to improving glycemic control, DDP-4 inhibitors might offer extra therapeutic value by controlling inflammation.Graphical Abstract
Source: European Journal of Clinical Pharmacology - September 22, 2023 Category: Drugs & Pharmacology Source Type: research

Skin and gut microbial associations with squamous cell carcinoma in solid organ transplant recipients
AbstractSolid organ transplant recipients (SOTRs) are burdened with a significantly higher risk of squamous cell carcinoma (SCC) compared to the general population. Accumulating evidence suggests the potential influence of microbial dysbiosis on transplant outcomes. Based on these observations, we sought to identify differences in the cutaneous and gut microbiomes of SOTRs with and without a history of SCC. This case –control study collected and analyzed non-lesional skin and fecal samples of 20 SOTRs >  18 years old with either ≥ 4 diagnoses of SCC since most recent transplant (n = 10) or 0 diagnoses o...
Source: Archives of Dermatological Research - September 22, 2023 Category: Dermatology Source Type: research

Posaconazole and risk of cutaneous squamous cell carcinoma after lung transplantation: a single institution, retrospective cohort study
Source: Archives of Dermatological Research - September 22, 2023 Category: Dermatology Source Type: research